5 foods to avoid when taking creon

Creon is a drug that is usually prescribed to people who have difficulty digesting food due to pancreatic enzyme deficiency. This medicine helps the body digest the fats, proteins, and carbohydrates in the food we eat. However, certain foods should be avoided while taking Creon to prevent possible side effects and ensure the drug works effectively. In this article, we will discuss 5 foods to avoid when taking creon.

Creon is a medicine used to manage exocrine pancreatic insufficiency (EPI). It contains digestive enzymes that are used to treat people with pancreatic enzyme deficiency, such as cystic fibrosis, chronic pancreatitis, or pancreatic cancer.

Too much Creon side effects certain foods. Below are 5 foods to avoid when taking creon:

1. High fat foods

High fat foods to avoid when taking creon. While taking Creon, it is important to avoid high-fat foods such as fried foods, fast food, fatty meats, and full-fat dairy foods. These foods are difficult to digest and require a lot of enzymes to break down, which can stress the digestive system. It can cause side effects like diarrhea, abdominal pain and nausea. It’s best to choose low-fat or lean options, such as lean meats, fish, and low-fat dairy products.

Below is a list of some high fat foods to avoid when taking creon

  • Beef (especially non-lean cuts)
  • Lamb
  • Poultry with the skin on
  • Pork
  • Fatty fish
  • Butter
  • Lard and cream
  • Cheese
  • Coconut (including coconut oil)
  • Some baked and fried foods
  • Ice cream
  • Palm oil and palm kernel oil

2. Salty food

Spicy foods can irritate the lining of the stomach and intestines, which can worsen digestive symptoms for those taking Creon. Spicy foods can also cause heartburn, which can be uncomfortable for people with pancreatic enzyme deficiencies. If you are taking Creon, avoiding spicy foods such as chili peppers, hot sauces, and curries is best.

3. High fiber foods

Although fiber is an important part of a healthy diet, it can be difficult for people with pancreatic enzyme deficiencies to digest. High-fiber foods such as whole grains, fruits, and vegetables can cause gas, bloating, and abdominal discomfort. It’s important to include fiber in your diet, but it’s best to choose low-fiber options like white bread, pasta, and cooked vegetables. So, High fiber foods to avoid when taking creon.

Raw fruits and vegetables are especially problematic because they contain high amounts of fiber that can be difficult for the body to break down. While taking Creon, it is best to avoid raw fruits and vegetables and opt for cooked or steamed options instead.

4. Alcohol

Alcohol can be very harmful to the digestive system, especially for those with pancreatic enzyme deficiencies. When taking Creon, it’s important to avoid alcohol. Because it can cause inflammation of the pancreas and interfere with the drug’s ability to break down and absorb nutrients from food.

5. Food processing

Processed foods like chips, cookies and frozen meals are often high in fat, salt, and sugar, which can be difficult for people with pancreatic enzyme deficiencies to digest. These foods can also be low in nutrients, which can worsen symptoms and lead to malnutrition over time. It’s best to choose whole, nutrient-dense foods like fresh fruits and vegetables, lean proteins, and whole grains.

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How long does Creon stay in your system?

The elimination half-life of Creon depends on several factors such as the individual’s metabolism, age, and health status. However, the half-life of Creon is generally estimated to be between one and two hours. This means that after one to two hours, half of the drug will be eliminated from the body. After five half-lives, about 5-10 hours after taking the drug, the drug is expected to be mostly eliminated from the body.

Will I gain weight on Creon?

Creon itself is not known to cause weight gain. Weight gain may occur in people with EPI who are taking Creon if their improved nutrient absorption leads to a positive caloric balance. However, weight gain is not a guaranteed result, and may not occur in all individuals with EPI who take Creon.


While taking Creon, it is important to avoid certain foods that creon side effects with the drug’s effectiveness. It is best to avoid high-fat foods, spicy foods, high-fiber foods, alcohol, and processed foods while taking Creon. Instead, choose whole, nutrient-dense foods that are easy to digest and will provide your body with the nutrients it needs to function properly. If you have any questions or concerns about your diet while taking Creon, be sure to talk to your healthcare provider.

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